Application Type
Invention
Application SubType
Invention PCT
(10) Registration Number and Date
Status
893/${sta2}
(180) Expiration Date
(20) Filing Number and Date
PH 1/2024/552182 2023.02.28
(40) Publication Number and Date
PH 1/2024/552182
U3
2025.02.10
(86) PCT Filing Number and Date
(87) PCT Publication Number and Date
(85) National Entry Date
(30) Priority Details
US 63/319,459
2022.03.14
(51) IPC Classes
(71/73) Applicant
(72) Inventor
(EN) BABB, Nicholas Alan : c/o ELI LILLY AND COMPANY P.O. Box 6288 Indianapolis
(EN) HERNANDEZ BUQUER, Selene : c/o ELI LILLY AND COMPANY P.O. Box 6288 Indianapolis
(EN) KAESER-WOO, Yea Jin : c/o ELI LILLY AND COMPANY P.O. Box 6288 Indianapolis
(74) Representative Name
(EN) AGCAOILI & ASSOCIATES : 7th Floor, BDO Towers Paseo, 8741 Paseo de Roxas
(54) Title
(EN) SARM1 RNA INTERFERENCE AGENTS.
(57) Abstract
(EN)
Provided herein are SARM1 RNAi agents and compositions comprising a SARM1 RNAi agent. Also provided herein are methods of using the SARM1 RNAi agents or compositions comprising a SARM1 RNAi agent for reducing SARM1 expression, reducing axon degeneration, and/or treating SARM1-mediated neurological disease in a subject.
(58) Citations