Application Type
Invention
Application SubType
Invention PCT
(10) Registration Number and Date
Status
PUBLISHED/${sta2}
(180) Expiration Date
(20) Filing Number and Date
PH 1/2024/550579 2018.06.08
(40) Publication Number and Date
PH 1/2024/550579
A1
2025.05.05
(86) PCT Filing Number and Date
(87) PCT Publication Number and Date
(85) National Entry Date
(30) Priority Details
(71/73) Applicant
(72) Inventor
(74) Representative Name
(EN) SyCip Salazar Hernandez & Gatmaitan : 105 Paseo de Roxas St.
(54) Title
(EN) ANTI TRBC1 ANTIGEN BINDING DOMAINS
(57) Abstract
(EN)
The present disclosure relates to anti-TRBCl antigen binding domains characterized by the sequences of the variable chains. The CDRs sequences of the variable chains are : (VH CDR1) GYTFT, (VH CDR2) NPYNDDIQS, (VH CDR3) GAGYNFDGAYRFFDF; and (VL CDR1) RSSQRLVHSNGNTYL, (VL CDR2) RVSNRFP, (VL CDR3) SQSTHVPYT. The claimed humanized antibodies derive from the murine JOVI antibody. Uses in cancer therapy.
(58) Citations
| Cited Documents | References | Category | Claims | Citation Type |
|---|---|---|---|---|
| 1.0 | WO 2015/132598 A1 (UCL BUSINESS PLC) 11 September 2015 | X | 1-13 | Patent |